PDX Models

At MuriPhys, we provide comprehensive preclinical oncology solutions to support the development of novel cancer therapeutics. We offer patient-derived xenografts (PDX), orthotopic tumor models, and advanced drug administration techniques that ensure high-quality, translationally relevant data for your oncology research.

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Patient-Derived Xenograft (PDX) Models

Patient-Derived Xenograft maintain patient tumor heterogeneity for clinically relevant drug response testing. Below is a list of available tumor cell lines commonly used by MuriPhys researchers:

Prostate Cancer: LNCaP​, PC-3​, DU-145
Breast Cancer: MCF-7​​, MDA-MB-231​, MDA-MB-468​, MDA-MB-453
Colorectal Cancer: HT-29​, HCT-116​, COLO 205​, SW620​, SNU-C2B​, KM12
Lung Cancer: NCI-H460, NCI-H522​, A549​, DMS53
Melanoma: SK-MEL-2​, A431​, A2058​, A375
Pancreatic Cancer: MIA-PaCa-2​, PANC-1
Ovarian Cancer: OVCAR-3​, SK-OV-3
Glioblastoma: U87-MG​, LN-229​, SF268​, U251​
Neuroblastoma: SK-N-MC​
Multiple Myeloma: MM.1S​, RPMI 8226​, OPM-2​
Acute Myeloid Leukemia: K562​, MOLM-13​, MV4-11

Animal Models - Nude Mice (Athymic Nude), SCID Mice, NSG Mice, NSG-HIS (Human Immune System models), BRGSF (Balb/c Rag2-/- IL2rg-/- SIRPα Tg). Contact us if you do not see your animal model. 

Advanced Drug Administration & Serial Injections

We specialize in the following routes of administration:

Intravenous (IV), Intramuscular (IM), Subcutaneous (SC), Intrathecal (IT), Intra Peritoneal (IP), Oral Gavage (PO), Topical, Slow-infusion and Continuous Infusions – Ensuring accurate systemic or localized therapeutic exposure.

Serial Injections – Enabling longitudinal drug administration studies to monitor treatment effects over time.

Quality Control: Mycoplasma Testing

To ensure the highest standards in preclinical research, all cell lines used in our studies undergo rigorous mycoplasma testing, preventing contamination and ensuring reliable, reproducible results.

At MuriPhys, we are dedicated to accelerating oncology drug discovery with cutting-edge preclinical solutions. Contact us today to discuss how we can support your oncology research!

Partner with Us to Advance Your Oncology Research
By choosing our comprehensive services, you gain a trusted partner committed to de-risking your projects and accelerating your path to clinical success. Contact us today to discover how we can empower your oncology research and help bring innovative therapies to patients faster.