Define the question
What needs to be learned before the next development decision?
Build Your Startup
Your science.
A team to build with.
Build the first evidence, prepare the research behind a grant, or find a place to do the work. Start with the support you need now.
U.S.-based in Durham, North Carolina.No foreign ties.
The next useful experiment
Turn a question
into evidence.
Bring your hypothesis, the evidence you have and the decision this study needs to inform. Work directly with our scientists on a relevant model, controls, endpoints and a practical scope.
Start with a focused experiment or build a coordinated sequence of studies. Consider suitable human cell models and NAMs alongside any justified animal work, with the 3Rs guiding the plan.
Discuss a proof-of-concept study Plan an in vivo proof of conceptChoose the evidence
Align the model, controls, methods and readouts with that question.
Agree on the work
Set readiness activities, deliverables, timing and a written scope.
The sequence illustrates study planning. Methods, study size and readiness work depend on the project.
SBIR/STTR & CDMRP research support
A research plan
you can put on paper.
Connect the experiments MuriPhys will perform with a practical budget, timeline and supporting documents. The same planning can carry into laboratory and in vivo execution after an award.
Discuss proposal support Outline the in vivo workShare the program, project stage, relevant aims and submission deadline. Sponsor eligibility and award decisions remain with the funding agency.
From the aims to the application
Review the proposed work together, resolve methods and resources, then align the quote and supporting materials with the application. Agree on preparation timing around the deadline.
Read our CRO and grant-planning insightNOV202026
One-day NIH SBIR/STTR writing workshop
Turn your idea into a workable application plan.
Join MuriPhys on November 20. Work on Specific Aims, connect the science to a budget, and see your proposal through a reviewer’s eyes.
Specific AimsStudy budgetsPartner planningMock NIH review
Research capacity in Durham, NC
A research base.
A team alongside yours.
Access shared bench and vivarium space with in vivo and in vitro equipment. Build a complete research setup around your program, with experienced scientists nearby.
When comparing vivarium rental options, include the equipment and scientific support needed to carry out the work. MuriPhys researchers can supplement your own team, add specialist expertise or execute agreed parts of a study.
Research you can build on
Find the capabilities for your next step.
Animal researchIn vivo & in-life studies
Dosing, in-life monitoring, longitudinal assessments and sample collection, guided by the 3Rs.
Explore animal research
CNS researchRobotic CNS delivery
Robotic stereotaxy, brain microdissection and study-specific CNS delivery approaches.
Explore CNS expertise
Functional assessmentsBehavioral assays
Motor, cognitive and sensory assessments connected to your model and research question.
Explore behavioral assays
Cell systemsiPSC & cell culture
Human iPSC-derived models and cell-culture work for NAM-informed study design and study-specific readouts.
Explore cell models
Sample readoutsMolecular & tissue assays
ELISA, PCR, ddPCR, IHC and immunofluorescence.
Explore laboratory assays
Cancer researchOncology research
Tumor models, treatment studies and tissue-based endpoints.
Explore oncology
Exposure & analysisPK & bioanalysis
Exposure, tissue distribution and coordinated analytical support.
Explore PK support- Ocular research
Ophthalmology
Ocular delivery, ERG, visual-function testing and disease-focused research.
Explore ocular research 
Functional recordingsIn vivo electro
physiology EEG, EMG and ERG readouts within an integrated preclinical study.
Explore electrophysiology
Neuroscience programsPreclinical neurobiology
Model selection, CNS administration and connected functional studies.
Explore neurobiology
Specialized researchRadiopharmaceutical research
Radioactive materials capabilities for preclinical research. Discuss the scope with our team.
Explore licensed capabilities
Build NAMs and the 3Rs into the plan.
Consider human cell models and other suitable NAMs early. Connect the evidence they can provide with any justified animal work, the study budget and your next milestone. Our scientists apply Replacement, Reduction and Refinement when planning animal research.
Our approach to NAMs and the 3RsBuild your next stage with us.
A scientific question, a first study or a funding deadline. Let’s work out the next step.