CNS drug delivery capability showcase
Robotic stereotaxy, regional delivery examples and connected functional readouts.
Explore resourceScientific resources
Explore the science.
White papers, capability notes, disease-model expertise and updates from MuriPhys. Find the methods and research examples relevant to your next experiment.
Interactive planning tool
Plan your next in vivo study.
Work through models, groups, treatments and connected readouts. Explore scientific considerations, save a draft and download a branded study plan to discuss with our team.
61 resources found
In vivo & in-life study services
Mouse and rat dosing, monitoring, longitudinal assessments, sampling and study reporting.
Explore resourceELISA, PCR, ddPCR & IHC assay services
Laboratory and tissue assays, method readiness, controls and connected study readouts.
Explore resourceIn Vivo Study Planner
Build a mouse or rat study outline with editable groups, treatment, measurements and sampling. Save it or send it to MuriPhys for scientific review and pricing.
Explore resourceStudy delivery, scope & pricing
Compare the scope, scientific fit, delivery and pricing factors for a MuriPhys study.
Explore resourceYour study brief
Save methods and evidence, then share a capability summary with your team.
Explore resourceShared bench & vivarium space
Shared bench and vivarium space with in vivo and in vitro equipment and researchers who can supplement your team.
Explore resourceResearch partnerships
Connect defined research contributions with CROs, laboratories, foundations and research programs.
Explore resourceCapability films
Short MuriPhys capability explainers and actual CNS laboratory work.
Explore resourceNAMs and the 3Rs
Human cell models, NAMs and appropriate animal studies at MuriPhys in NC. Our commitment to Replacement, Reduction and Refinement guides study planning.
Explore resourceiPSC models & cell culture
Human iPSC models, cell culture and NAMs in Durham, NC. Sensory-neuron, viability, gene-expression and oxidative-stress studies with MuriPhys.
Explore resourceMotor disorder research
Connect disease models with delivery, gait, coordination and neuromuscular readouts.
Explore resourceCNS delivery capabilities
Robotic stereotaxic CNS delivery and brain microdissection, with representative AAV distribution and expression images.
Explore resourceRotarod assessment of ethanol effects
A motor-coordination study illustrating a dose-dependent behavioral readout in mice.
Explore resourcePreclinical drug development
An overview of study planning, preclinical services, execution and reporting.
Explore resourceMechanisms of episodic ataxia
Research on stress-induced motor attacks and cerebellar signaling in the tottering mouse.
Explore resourceAAV-mediated CRISPR research in Huntington’s disease
A research example involving striatal delivery, promoter selection and mutant huntingtin in BACHD mice.
Explore resourcePartner early: planning SBIR/STTR research with a CRO
Plan SBIR/STTR research with a CRO. Connect models, NAMs, scientific scope, budget inputs, facilities and study execution with your startup milestone.
Explore resourceBehavioral assays
Rodent motor, cognitive, social and sensory assessments at MuriPhys, including rotarod, BlackBox One, Noldus CatWalk and study-specific functional tests.
Explore resourceIn vivo electrophysiology
Connect EEG, EMG and ERG with rodent behavior, CNS delivery and biological endpoints. Plan study-specific electrophysiology with MuriPhys in NC.
Explore resourceLC-MS bioanalysis and PK support
Coordinate LC-MS and LC-HRMS bioanalysis with MuriPhys. Connect PK sampling, analytical methods, study readiness and specialist laboratory support.
Explore resourceOncology models
MuriPhys oncology study support connects CDX, PDX, syngeneic and engineered models with dosing, tumor measurements, imaging and tissue endpoints.
Explore resourceOncology radiopharmaceutical research
Discuss radiolabeled compounds, biodistribution and oncology studies with MuriPhys. Materials, methods and licensed activities are scoped for each project.
Explore resourceOphthalmology
Preclinical ocular delivery, OCT imaging, optomotor testing and Celeris ERG at MuriPhys. Connect structural and functional readouts with your study.
Explore resourcePharmacokinetics and drug metabolism
Plan rodent PK studies with MuriPhys. Coordinate administration, sampling, tissue distribution, metabolic collection and specialist bioanalysis.
Explore resourceRobotic stereotaxic CNS delivery & brain microdissection
Robotic stereotaxic surgery, CNS drug delivery and brain microdissection in rodents. Explore IPa, ICV, intrathecal, cisterna magna and CED studies.
Explore resourceConnected preclinical neurobiology
MuriPhys connects rodent-model selection, robotic CNS delivery, behavioral assays and functional measurements with your neurobiology research question.
Explore resourceBuild your startup
Build with MuriPhys: proof of concept, SBIR/STTR support, shared bench and vivarium space, in vivo and in vitro equipment, and researchers alongside your team.
Explore resourceRare CNS disorders
Research support for Huntington’s, Parkinson’s, ataxia, ALS, Rett and related CNS conditions, with study-specific delivery and functional readouts.
Explore resourceDementia research
Study Alzheimer’s, vascular, Lewy body and frontotemporal dementia with MuriPhys. Connect relevant models, CNS delivery and functional assessments.
Explore resourceEye disease research
MuriPhys ocular research covers retinal degeneration, glaucoma and FECD with study-specific delivery, OCT imaging and visual-function assessments.
Explore resourceLiver disease research
Preclinical support for Wilson’s disease, hemochromatosis and familial hypercholesterolemia, connecting delivery with appropriate disease-specific readouts.
Explore resourceNeurodegenerative disorders
Connect CNS delivery, behavioral assays and electrophysiology for Huntington’s, Parkinson’s, ALS and ataxia research with the MuriPhys scientific team.
Explore resourceNeurodevelopmental disorders
MuriPhys supports model-based research relevant to autism, Fragile X and Rett syndrome through CNS delivery and study-specific functional assessments.
Explore resourceNeuropsychiatric disorders
Research support for schizophrenia, anxiety and dementias at MuriPhys, connecting suitable models with CNS delivery, behavior and electrophysiology.
Explore resourceOncology disease models
Plan preclinical cancer studies with MuriPhys. Connect cell-based and animal models with tumor growth, treatment response, immune and biomarker endpoints.
Explore resourcePain research
MuriPhys supports neuropathic, inflammatory and visceral pain research through study-specific delivery, behavioral assays and functional measurements.
Explore resourceSubstance-use research
Preclinical substance-use research at MuriPhys, including dependence, withdrawal and treatment-response questions with selected models and readouts.
Explore resourceAmyotrophic lateral sclerosis (ALS)
MuriPhys research support for ALS connects appropriate rodent models, CNS delivery, motor assessments and functional measurements with your study question.
Explore resourceAtaxia research
Explore MuriPhys ataxia research, including cerebellar CNS delivery, motor and gait assessments, electrophysiology and the episodic-ataxia white paper.
Explore resourceFuchs endothelial corneal dystrophy (FECD)
Discuss FECD research with MuriPhys. Connect ocular delivery, corneal imaging and appropriately selected visual-function endpoints with your model.
Explore resourceHuntington’s disease research
MuriPhys supports Huntington’s disease research through targeted CNS delivery, motor and cognitive assessments and relevant biological readouts.
Explore resourceInflammatory pain research
Study inflammatory pain with MuriPhys. Connect administration, plantar and von Frey tests, functional assessments and suitable study-specific readouts.
Explore resourceNeuropathic pain research
Explore MuriPhys neuropathic-pain research support, including delivery, plantar and von Frey testing, weight bearing and appropriate functional readouts.
Explore resourceOpioid-use research
Discuss preclinical opioid-use research with MuriPhys. Select delivery, behavioral, withdrawal and functional readouts for the model and research question.
Explore resourceParkinson’s disease research
MuriPhys supports Parkinson’s research with robotic CNS delivery, motor assays and electrophysiology. Define the target, model and study endpoints.
Explore resourceRett syndrome research
MuriPhys Rett syndrome research support connects CNS delivery, model-specific behavioral assessments and appropriate EEG and neuromuscular readouts.
Explore resourceSchizophrenia research
Plan model-based schizophrenia research with MuriPhys. Coordinate CNS delivery, behavioral tests, EEG and study-specific functional measurements.
Explore resourceVisceral pain research
MuriPhys supports visceral-pain research with study-specific models, CNS or systemic delivery, behavioral assessments and functional endpoints.
Explore resourceWilson’s disease research
Connect delivery, biochemical and tissue endpoints, motor assessments and selected functional readouts for Wilson’s disease research with MuriPhys.
Explore resourceMuriPhys and Qmera connect in vivo research and bioanalysis
The July 2025 MuriPhys–Qmera collaboration announcement connects in vivo study execution, pharmacokinetics and coordinated bioanalytical support.
Explore resourceMuriPhys and Vitality Robotics: necropsy workflow collaboration
Read the MuriPhys–Vitality Robotics collaboration announcement on necropsy workflows, laboratory automation and research-data integration.
Explore resourceRadioactive materials license
MuriPhys radioactive materials licensing supports scoped radiopharmaceutical, biodistribution and oncology research. Discuss your study with our team.
Explore resourceAAALAC accreditation and commendation
Read MuriPhys’s March 2025 AAALAC accreditation announcement and Council commendation of its laboratory animal care and use program.
Explore resourceBiomarker discovery and molecular profiling
MuriPhys coordinates tissue collection, IHC, immunofluorescence and specialist genomic or proteomic workstreams for preclinical biomarker research.
Explore resourceCell line-derived xenograft models
Plan CDX research with MuriPhys, from tumor-cell and mouse-model selection through implantation, dosing, tumor monitoring, imaging and tissue analysis.
Explore resourceRadiopharmaceutical research
MuriPhys radiopharmaceutical research support connects licensed activities, radiolabeled compounds and appropriate biodistribution or oncology endpoints.
Explore resourceGenetically engineered mouse models
MuriPhys supports genetically engineered tumor-model studies with colony planning, imaging, physiological monitoring and coordinated study execution.
Explore resourceMetastatic cancer models
Discuss metastatic oncology research with MuriPhys. Plan syngeneic, xenograft or engineered models, implantation, treatment and study-specific imaging.
Explore resourcePatient-derived xenograft models
Discuss PDX study requirements with MuriPhys, including patient-derived material, model readiness, implantation, dosing and treatment-response endpoints.
Explore resourceSyngeneic tumor models
MuriPhys supports syngeneic tumor studies in immunocompetent mice. Connect model and strain selection with treatment, tumor monitoring and immune readouts.
Explore resourceNo matching resources. Try a different method or model, or ask a scientist.
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